Multi-linked Stainless Steel Bioreactor

Nominal volume: 5 sets of 50 liters, can have a transplanting workstation, each tank can be controlled independently, each tank can be connected in parallel for parallel comparison process, can also be connected in series for metabolic flow study, centralized computer analysis and control

Diameter-to-height ratio: 1:2-3; Liquid charging factor: 70%

Tank: 316L stainless steel tank

Mixing method: Shaft drive mechanical mixing (John Crane mechanical seal)

Ventilation: The rotameter shows that the flow rate of the gas is adjusted according to the process requirements

PH control function: intelligent PID control, METTLER PH electrode;

DO function: METTLER DO electrode can be controlled in association with feeding and rotational speed.

Temperature control: intelligent PID control, electric heating, water cooling

Feeding: perfect feeding system (acid, alkali, bubble enemy, culture agent), can be programmed to control the feeding;

Sterilization: Sterilization in situ;

Vaccination: Alcohol flame inoculation and transplantation workstation transplantation

Technical Parameters:

Stirring speed: special speed regulating motor, wide range, low noise, high temperature resistance, speed: 50~1000rpm Accuracy: ±1rpm;

PH control: intelligent PID control, peristaltic pump automatically replenishes acid/alkali; Range: 2~12ph; Control accuracy: ±0.02ph,

DO control: intelligent PID control, which can be associated with the feeding speed; Range: 0~100%, Control accuracy: ±3%;

Temperature control: intelligent PID control; Electric heating, water cooling; Range: cooling water temperature +5~60°C; Accuracy: ±0.1°C;

Foam control: electrode detection, peristaltic pump replenishment defoamer, automatic control;

Ventilation: manual adjustment, flow meter display;

Tank pressure: manual adjustment, pressure gauge display; Range: 0~0.20Map;

BLBIO-C type control system: Siemens S7-200 series PLC control system + Advantech industrial control computer, full Chinese menu and interface; You can use the USB disk for data transmission, sampling and display of tank data, browsing and analysis of system data, and reading settings.

BLBIO-8.0 analysis software: Based on the theory of detection and control of biological metabolic flow of cells and molecules and the optimization of microbial fermentation process for many years, it has rich biological fermentation process detection software, with rich sampling. The main functions of this software are as follows:

A: Accurately calculate indirect parameters such as OUR, CER, RQ, KLa and other online parameters, and can display multiple curves with different parameters on the same coordinate plane at the same time;

B: Accurately display the material balance and changes in the fermenter, which is convenient for users to analyze the correlation of the fermentation process, so as to help users derive appropriate control points and achieve the purpose of one-step scale-up of pilot test;

C: It can input the detection data of total sugar, reducing sugar, amino nitrogen, bacterial concentration, fermentation unit and other offline and generate the corresponding curve under the online process parameter curve;

D: It mainly has the following functions:

Parallel sampling of multiple tanks

Direct comparison of multi-batch data

Unified display and comprehensive analysis of multiple data

Convenient customization capability (can be programmed by yourself)

Real-time sampling of online data

Real-time processing and display of online data

Manual parameter input

Indirect parameters are automatically calculated

Historical data query and display

Custom parameters

Graphics, report printing

This equipment is a relatively high-end product developed by our company, which is suitable for large-scale pharmaceutical factories and research institutes to optimize the process