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Two-stage Double Bioreactor

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Two-stage Double Bioreactor


BLBIO-10SJ-10SJ-10SJ-50SJ 10L10L 10L50L secondary double fermenter


15L15L50L100L multi-stage fermenter BLBIO-15SJ-15SJ-50SJ-100SJ


BLBIO-30SJ-100SJ-1000SJ-2000SJ


Multiple fermenters (with or without different volumes) can be used to form a conjoined system, which is suitable for parallel orthogonal tests, providing an optimal approach to process research and shortening valuable research time. The key is that the process parameters of this equipment configuration are relatively repeatable.


Diameter-to-height ratio: 1:2.5; Liquid charging factor: 70%

Tank: the main body is made of stainless steel 316L tank, no dead angle in the tank; It is equipped with special sampling and discharging valves for fermentation tanks and seed transfer pipelines. Using a large viewing angle tank liquid level observation glass, 12V safety lamp, with temperature, PH, DO, defoaming, liquid level interface, inoculation port, feeding port, and multiple spare ports, all welds are firm, neat and beautiful.

Tank: design pressure 0.35Mpa Jacket: design pressure 0.3Mpa, using optimized diversion design, improve the exchange efficiency and the uniformity of temperature in the tank

Tank function: John Crane mechanical seal, air intake sterilization filter, exhaust condenser, air intake system with air distributor, flame inoculation port (also feeding port and cleaning port), discharge port, sampling port, feeding port; The five electrodes with automatic control parameters are: PH electrode, DO electrode, defoaming electrode, and temperature electrode mouth; Each tank has four peristaltic pumps that automatically control the replenishment of acid/alkali/bubble enemy/culture agent respectively;

Motor: SEW AC motor to ensure that the motor can operate in harsh environments;

Ventilation: a deep ventilation is adopted, the rotameter displays, the flow rate of gas is adjusted according to the process requirements, and the air distributor in the tank is evenly distributed; Sterilization filters with an accuracy of 0.2μm (Dominica or Shanghai Yiming) are adopted, and there is an anti-backflow device to ensure safety and greatly extend the service life;

Mixing system: mechanical mixing system, John Crane mechanical seal, Fujifilm inverter

Mixing form: straight blade stirring paddle (second stage), inclined blade stirring paddle (first stage), mechanical compression defoaming paddle (first stage), four material baffle plates;

Fermentation pH control function: intelligent PID control, dedicated Swiss METTLER PH electrode;

Fermentation dissolved oxygen degree control function: intelligent PID control, dedicated Swiss METTLER DO electrode;

Temperature control: electric heating, water cooling, circulating pump circulating temperature control, air self-escape function and water cut-off, over-temperature protection function, with good heat exchange efficiency; The intelligent module control not only ensures the speed of temperature control, but also realizes energy saving.

Feeding: perfect feeding system (acid, alkali, bubble enemy, culture agent), can be regularly and quantitatively fed; Each of the four peristaltic pumps can be set in sections on the control interface, which is convenient and flexible in actual use. Equipped with specially designed feeding pins to ensure the safe operation of feeding;


Working volume: 5L, 7L, 10L, 15L, 20L, 30L, 50L, 100L、、、、、 10000L

The control system and the volume of the fermenter can be combined in any way, which is convenient and flexible

Add optional features:

b. Feeding balance weighing W Tank weighing D Automatic control of air flow e Tank pressure detection f Bypass pure oxygen g On-line detection of redox potential h On-line detection and control of methyl (ethyl) alcohol content I On-line detection of exhaust gas O2 and CO2 content A Automatic sterilization function C. Automatic tank cleaning function U. Automatic lifting function of tank cover

Model note: BLBIO-XABC-D

X—total tank volume:

A—Tank Material:-G: Glass/-S: Stainless Steel -C Animal Cell Tank -V Vaccine Tank -M Enzyme Reactor

B—Transmission mode: -C: Magnetic transmission mechanical stirring/-J direct transmission mechanical stirring/-Q air flow stirring, -S solid stirring, -L provides light source

C --Add optional function -A automatic sterilization -Manual sterilization without wei -Y Glass in-situ manual sterilization -U Automatic lifting of the tank lid

D -- Controller model -A is an industrial control computer + control module -Wuwei B type controller, which is our company's standard controller -C is a floor-standing 10-inch LCD touch screen + PLC -D is a 15-inch LCD touch screen + Siemens PLC + imported transmitter


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