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Three-stage Automatic Bioreactor

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Three-stage Automatic Bioreactor


BLBIO-5SJ-50SJ-500SJ 5 liters 50 liters 500 liters grade 3 stainless steel fermenter


BLBIO-10SJ-50SJ-700SJ 10 liters 50 liters 700 liters grade 3 stainless steel fermentation tank


BLBIO-50SJ-500SJ-5000SJ 50 liters 500 liters 5000 liters grade 3 stainless steel fermenter


BLBIO-100SJ-100SJ-1000SJ 100 liters 1000 liters 1000 liters grade 3 stainless steel fermenter


In the multi-stage fermenter system, each tank can be used independently or in combination; Reliable seed transfer line, can be sterilized separately; Floor-mounted/bench-mounted rack optional, BLBIO-A, B, C, D control system optional: separate control cabinet or centralized control; Various fermenters can be combined as required, and are suitable for experimental studies of transition fermentation from laboratory shake flask scale-up to production, as well as for small-scale production

BLBIO-C type control system: German Siemens S7-200 series PLC control system +10" LCD touch screen display operation, on-site direct operation (menu type), full Chinese menu and interface; Sampling and display of tank data, browsing and analysis of system data, reading settings. It can control the stirring speed, the temperature of the medium in the tank, the pH value, and the DO value;

It can set the upper and lower limits of temperature, speed, PH value, DO value, and has the function of over-limit alarm;

It has the functions of over-level alarm and automatic refill, over-level alarm and automatic addition of defoamer;

All alarm accidents can be recorded and consulted;

Speed, temperature, PH value, DO value, etc. can be set to automatic and off state;

Parameters such as medium temperature, stirring speed, Ph, DO and other parameters in the tank can be set and controlled in sections according to the process requirements;

Each parameter has PID adjustment process display, such as set value, real-time value, PID set value, upper and lower limit value, curve display, manual/automatic switching, online setting, etc.;

The historical data and curves of various parameters can be stored for many years, and the real-time curves can be restored as they are when the power is turned on again;

The man-machine interface is friendly, and more than a dozen monitoring screens can be switched;

It has the function of feeding and metering; Regular and quantitative feeding;

The system has a variety of correlation controls: correlation control between velocity and dissolved oxygen, correlation control between feeding and dissolved oxygen, correlation control between feeding and pH value, etc.;

The system has real-time display, data recording and data analysis of the running process

The parameters of each detection and control loop can be manually set and corrected online on the screen, and the temperature, DO, PH sensors can be set and adjusted, and the flow rate of each peristaltic pump can be calibrated. The operation has a password protection function, and the password is divided into operator and administrator-level passwords;

Automatically record the fermenter start-up time, shutdown time, number of power outages during automatic operation, power outage time, call time, etc.;

The software system has self-adaptive and self-diagnostic capabilities;


Scale: 5L-30L-100L/5L-50L-300L/5L-50L-500L/10L-100L-1000L/50L-500L-5000L

Nominal volume: 5L-50L-500L;

Diameter-to-height ratio: 1:2-3; Liquid charging factor: 70%

5 liters 50 liters 500 liters tank: the main body is made of stainless steel 316L tank, and there is no dead angle in the tank; It is equipped with special sampling and discharging valves for fermentation tanks and seed transfer pipelines. Using a large viewing angle tank liquid level observation glass, 12V safety lamp, with temperature, PH, DO, defoaming, liquid level interface, inoculation port, feeding port, and multiple spare ports, all welds are firm, neat and beautiful.

Tank: design pressure 0.3Mpa Jacket: design pressure 0.3Mpa, using optimized diversion design, improve the exchange efficiency and the uniformity of temperature in the tank

Tank function: John Crane mechanical seal, air intake sterilization filter, exhaust condenser, air intake system with air distributor, flame inoculation port (also feeding port and cleaning port), discharge port, sampling port, feeding port; The five electrodes with automatic control parameters are: PH electrode, DO electrode, defoaming electrode, and temperature electrode mouth; Each tank has four peristaltic pumps that automatically control the replenishment of acid/alkali/bubble enemy/culture agent respectively;

Motor: AC motor for fermenter to ensure that the motor can operate in harsh environments;


Add optional features:

b. Feeding balance weighing W Tank weighing D Automatic control of air flow e Tank pressure detection f Bypass pure oxygen g On-line detection of redox potential h On-line detection and control of methyl (ethyl) alcohol content I On-line detection of tail gas O2 and CO2 content A Automatic sterilization function C. Automatic tank cleaning function U Automatic lifting function of tank cover


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