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Mammalian Stainless Steel Bioreactor (20L-5000L)

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Mammalian Stainless Steel Bioreactor (20L-5000L)


100L animal cell bioreactor


100L Animal Cell Bioreactor BLBIO-100SCCU


300L Animal Cell Bioreactor (Upper Magnetic Stirring System) BLBIO-300SCUC


500L Animal Cell Bioreactor (Upper Magnetic Stirring System) BLBIO-500SCUC



Parameter

Description

Total volume

5L,10L,15L,20L,30L,50L,100L,200L,500L,1000L, 5KL, 10KL etc.

Working volume

30%~70%

Tank

Inside electrolytic polishing, precision: 0.2-0.4um. Diameter and height ratio 1:1.5

Stirring system

Magnetic drive, low shear mixing blades. Stir speed: 30~300rpm

Sterilization

Sterilize in place (SIP), auto control by program

Clean

Clean in place by spray ball

Gas control

Provision for mixing at least four gases (Air, Oxygen, Nitrogen and CO2) Auto control by mass flow meter. Air flow 1vvm, O2/N2/CO2  0.1vvm.

Feeding

Automatically feeding by peristaltic pump

Anti-foam control

Automatically add antifoamer by peristaltic pump

Temperature control

Auto-control, electric heating range: water source add 5℃ to 70℃

PH control

PH 2.00-12.00±0.1, auto-control adding acid/base by peristaltic pump, pH sensor from Hamilton/Mettler, Switzerland.

Do control

0-150±3% displaying precision 0.1%, DO sensor from Hamilton/Mettler, Switzerland. DO coupling with agitation, oxygen.

Sampling valve

Can sterilization separately, manual

Harvest

Zero dead zone bottom valve, can sterilization separately, manual

Weight system

Mettler-Toledo, Switzerland

Pressure

Auto control, BD Germany pressure transmitter or Lambert differential pressure liquid level gauge.

Exhaust

Have condenser before exhaust, control by diagram valve / Proportional control valve.

Control parameters

10 or 15 inch touch screen, Siemens PLC with control parameters (stirring, pH, DO, temperature, feeding, alarm, gas etc.), data analysis, data record, data output, language(RU/EN/CN) and other customized functions

Optional configuration

Remote control, Mass flow meter(auto control gas), exhaust heating, exhaust filter, gas(CO2) exhaust analysis, Level sensor, Turbidity(OD) sensor, ORP sensor, Weight system, Live cell sensorBiomass, Printing, Siemens touch screen, Double mechanical seal, 4-valves-group for feeding, Bottom valve auto, ASME certificate, CSA certificate, air flow 2vvm, etc.

Fermenter Description:

BLBIO GJ series fermentation system is a set of laboratory glass fermentation equipment with powerful functions, which can meet various purposes of fermentation, such as batch, batch fed, and even animal cell culture.

The 10inch color touch screen is used to display all measured values and control parameters, which greatly facilitates the user’s operation. 4 peristaltic pumps are installed on the front of the control box, which can replenish acid, alkali, defoamer and medium to the fermenter.

Various parameters in fermentation such as pH, DO, temperature and rotational speed can be monitored by the controller, and all data and control parameters can be transmitted to the controller or computer.

The structure is compact, and various components can be integrated on the fermentation system.

The upper-driven direct-coupling mechanical stirring ,with simple structure and stable operation.

Fermenter Application:

  1. Animal vaccine production:

    Avian influenza vaccine, Porcine PRRS vaccine, Foot-and-mouth disease, Rabies vaccine, Mink vaccine, DTP vaccine, Diphtheria vaccine, Tetanus vaccine, etc.

  2. Human vaccine production:

    Diphtheria vaccine, Tetanus vaccine, Meningitis vaccine, Pneumonia IV vaccine, Hepatitis B vaccine, etc.

  3. Culture for microorganism (bacterial,fungi,yeast.etc), mammalian cell(293,CHO etc.), plant cell, algae, enzyme, pro


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