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Fully Automatic Vaccine Fermenter

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Fully Automatic Vaccine Fermenter


10L100L2 automatic vaccine fermenter BLBIO-10V-100V


30L200L Vaccine Fermenter BLBIO-30V-200V


50L500L Automatic Vaccine Fermenter BLBIO-50V-500V


100L900L Automatic Vaccine Fermenter BLBIO-100V-1000V


50 liters 1000 liters secondary automatic bacterial vaccine fermenter BLBIO-50V-1000V


5000L Automatic Vaccine Production Line BLBIO-5000V


BLBIO-XSCV/SJV/SJBV(X means volume liters) is a pilot/industry size vaccine production fermenter.It meet cGMP standards, and ability to offer relative verification documents.  

Easy operation and clean. All liquid contact part is SS316L. 

Standard model control pH/DO/foam/temperature/agitation/4 gas, four-valve feeding system, tank poshing 0.2um-0.4um, sanitary sampling system, gas auto control by mass flow meter optional. 

Control panel language EN/CN/RU. Accept customize and design.


Parameter

Description

Total volume

5L,10L,15L,20L,30L,50L,100L,200L,500L,1000L, 2KL,5KL,10KL etc.

Working volume

30%~70%

Polishing

Electrolytic polishing, precision: 0.2-0.4um.

Stirring system

Mechanical drive or Magnetic drive, 3 height adjustable six – blade stirrer Stir speed: 50~1000rpm/50-350rpm

Sterilization

On-site sterilization(SIP) by auto control

Clean

Clean in place (CIP) by spray ball

Aeration flow

Multi-way ventilation. Auto control by mass flow meter, 1vvm

Feeding

Automatically feeding by fixed peristaltic pump (standard) Variable speed peristaltic pump(optional)

Anti-foam control

Automatically add antifoam by peristaltic pump

Temperature control

Auto-control, electric heating range: water source add 5℃ to 70℃

PH control

2.00-12.00±0.05pH, auto-control by adding acid and base, pH sensor (Hamilton/Mettler, Switzerland)

DO control

0-150±3% displaying precision 0.1%, DO sensor from Hamilton/Mettler, Switzerland. DO coupling with agitation, oxygen.

Sampling valve

Can sterilization separately, manual

Harvest

Zero dead zone bottom valve, can sterilization separately, manual

Weight system

Mettler-Toledo, Switzerland

Pressure

Auto control, BD Germany pressure transmitter or Lambert differential pressure liquid level gauge.

Exhaust

Have condenser before exhaust, control by diagram valve / Proportional control valve.

Control parameters

10in touch screen, Siemens PLC control system with control parameters (stirring, pH, DO, temperature, feeding, gas etc.), data analysis, data logging, data output and printing, overrun alarm, language switching and other functions

Optional configuration

O2/N2/CO2 gas control, Level sensor, OD sensor, Turbidity sensor, ORP sensor, Weight system, Live cell sensor etc.

Fermenter Description:

BLBIO GJ series fermentation system is a set of laboratory glass fermentation equipment with powerful functions, which can meet various purposes of fermentation, such as batch, batch fed, and even animal cell culture.

The 10inch color touch screen is used to display all measured values and control parameters, which greatly facilitates the user’s operation. 4 peristaltic pumps are installed on the front of the control box, which can replenish acid, alkali, defoamer and medium to the fermenter.

Various parameters in fermentation such as pH, DO, temperature and rotational speed can be monitored by the controller, and all data and control parameters can be transmitted to the controller or computer.

The structure is compact, and various components can be integrated on the fermentation system.

The upper-driven direct-coupling mechanical stirring ,with simple structure and stable operation.

Fermenter Application:

  1. Animal vaccine production:

    Avian influenza vaccine, Porcine PRRS vaccine, Foot-and-mouth disease, Rabies vaccine, Mink vaccine, DTP vaccine, Diphtheria vaccine, Tetanus vaccine, etc.

  2. Human vaccine production:

    Diphtheria vaccine, Tetanus vaccine, Meningitis vaccine, Pneumonia IV vaccine, Hepatitis B vaccine, etc.

  3. Culture for microorganism (bacterial,fungi,yeast.etc), mammalian cell(293,CHO etc.), plant cell, algae, enzyme, pro


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