Fully Automatic Bioreactor

Diameter to height ratio: 1:2-3; Filling coefficient: 70%

500 liter tank body: The main material is a 316L stainless steel tank body, with no dead corners inside the tank; Equipped with dedicated sampling and discharging valves for fermentation tanks, as well as transfer pipelines. Adopting a large angle liquid level observation mirror inside the tank, 12V safety light, with temperature PH、 DO、 Defoaming, liquid level interface, inoculation port, feeding port, and multiple spare ports, all welds are sturdy, neat, and aesthetically pleasing.

Tank body: design pressure 0.3Mpa, jacket: design pressure 0.3Mpa, optimized flow design, improved exchange efficiency and uniformity of temperature inside the tank

Tank functions: John Crane mechanical seal, inlet sterilization filter, exhaust condenser, inlet system with air distributor, flame inoculation port (also feeding and cleaning port), discharge port, sampling port, and feeding port; The five electrodes for automatic control parameters are: pH electrode DO electrode, defoaming electrode, temperature electrode port; Four peristaltic pumps are automatically controlled to replenish acid/alkali/foam/culture medium respectively;

Motor: Special SEW AC motor for fermentation tanks, ensuring that the motor can operate in harsh environments;

Ventilation: Adopting a deep ventilation system with a rotor flow meter display, adjusting the gas flow rate according to process requirements, and evenly distributing gas through the air distributor inside the tank; Adopting a sterilization filter with an accuracy of 0.2 μ m (Dominic or Shanghai Yiming), equipped with an anti material backflow device, ensuring safety and greatly extending service life;

Mixing system: Mechanical mixing system, SEW AC motor, Fuji frequency converter

Mixing form: straight blade mixing blade (second stage) inclined blade mixing blade (first stage), mechanical compression defoaming blade (first stage), four baffle plates;

Fermentation pH control function: using intelligent PID control, dedicated Swiss Mettler PH electrode;

Fermentation dissolved oxygen control function: adopting intelligent PID control, dedicated Swiss Mettler DO electrode;

Temperature control: electric heating, water cooling, circulating pump temperature control, with air escape function and water cut off and over temperature protection function, with good heat exchange efficiency; The intelligent module control ensures both the speed of temperature control and energy conservation.

Supplementing: A comprehensive feeding system (acid, alkali, foam, culture agent) that can be used for timed and quantitative feeding; The four peristaltic pumps can be set in segments on the control interface, making them convenient and flexible for practical use. Equipped with specially designed feeding pins to ensure safe operation of feeding;

Pressure detection: Swiss transmitter automatically detects tank pressure and releases pressure automatically

Automatic lid lifting system (optional): BLBIO-UIP500 automatic lid lifting system uses an electric system to lift the lid for easy cleaning and maintenance of equipment inside the tank

Sterilization method: BLBIO-SIP automatic program sterilization (leading technology, stable quality, low failure rate, reducing operator labor intensity)

Temperature: Cooling water temperature+5 ℃~80 ℃ ± 0.2 ℃, cooled with tap water or ice water, external circulation heating, to avoid local overheating, and temperature control stability.

PH: 2.00~12.00 ± 0.05 Two peristaltic pumps bidirectional switch control

DO: 0-100% ± 3%

Mixing: 50~1000rpm ± 10% stepless speed regulation, axial transmission mechanical mixing or magnetic transmission mechanical mixing

Replenishment: peristaltic pump duty cycle switch control

Defoaming: Sensitivity 100-100000 Ω electrode detection, peristaltic pump duty cycle switch control for adding defoamer

Pressure: Automatic pressure detection

BLBIO-S control system optional: Siemens S7-200 series PLC control system, mature, stable, and universal PLC, suitable for various automation applications, especially in production and manufacturing process control. The Siemens PLC control core has become an economical and advanced control system in the implementation of biological reaction process control due to its modularity, easy implementation of distributed configuration, and easy mastery. The system uses a 10 inch or larger tablet computer to control pH DO、 Seven direct parameters, including tank pressure, temperature, rotational speed, defoaming, and replenishment, as well as the automatic sterilization process of the tank pipeline, can be conveniently calibrated for pH through software DO electrode; Set the initial control state of the parameters

Add optional features:

b   Supplementing balance weighing W tank weighing D automatic air flow control E tank pressure detection F bypass pure oxygen g   Online detection of redox potential h    Online detection and control of A (B) alcohol content in tail gas O2 CO2 content online detection A automatic sterilization function C automatic tank cleaning function Automatic lifting function of U can cover

Model annotation: BLBIO XABC-D

X - Total tank volume:

A - Tank material: - G: glass/- S: stainless steel - C animal cell tank - V vaccine tank - M enzyme reactor

B - Transmission mode: - C: Magnetic drive mechanical stirring/- J direct drive mechanical stirring/- Q airflow stirring - S solid stirring - G provides light source

C -- Add optional functions - A Automatic sterilization - No manual sterilization - Y Glass in-situ manual sterilization - U Can lid automatic lifting

D - Controller model - A is an industrial control computer+control module - None is a B-type controller, which is our company's standard controller - C is a 10 inch LCD touch screen+PLC - D is a 15 inch LCD touch screen+Siemens PLC+imported transmitter